SCHEMBL6712439

SCHEMBL6712439

CC(=O)OC1CC(C)CCC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
RIPK3 Q9Y572 1/20 0.38
HSD11B1 P28845 3/20 0.36
ACHE P22303 1/20 0.35
TSHR P16473 1/20 0.33
PLA2G2A P14555 2/20 0.32
TRPM2 O94759 1/20 0.32
PAX8 Q06710 1/20 0.32
F10 P00742 2/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9632895 0.83 ALDH1A1 (0.31)
SCHEMBL28115965 0.82 CYP3A4 (0.50) CYP3A4RIPK3HSD11B1ACHEPAX8
SCHEMBL7641385 0.80 CYP2C19 (0.31)
SCHEMBL19788616 0.77 CYP3A4 (0.38) CYP3A4RIPK3HSD11B1ACHEPLA2G2A
SCHEMBL2158606 0.76 ALOX5 (0.32) CYP3A4HSD11B1TSHRPAX8
SCHEMBL14905851 0.76
SCHEMBL7739923 0.74
SCHEMBL3857214 0.74 CYP3A4 (0.41) CYP3A4HSD11B1ACHE
SCHEMBL27831207 0.73 CYP3A4 (0.43) CYP3A4HSD11B1ACHEPLA2G2ATRPM2
SCHEMBL18264956 0.72 CYP3A4 (0.39) CYP3A4RIPK3HSD11B1ACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1108703-B1 Fragance composition TAKASAGO PERFUMERY CO LTD (JP) 2004-03-10 EP disclosed
US-6489273-B1 Fragrance compositions containing 2-cyclohexyl-1,1-dimethyl ethanol esters TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-12-03 US disclosed