Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711541 | 0.90 | HIF1A (0.41) | HIF1ANPSR1RXFP1F10ALDH1A1 | |
| SCHEMBL6708039 | 0.90 | F10 (0.40) | F10ALDH1A1TSHRHTTROCK1 | |
| SCHEMBL6712532 | 0.89 | NPSR1 (0.41) | HIF1ANPSR1RXFP1ALDH1A1TSHR | |
| SCHEMBL6710330 | 0.87 | CNR2 (0.39) | F10ALDH1A1TSHRHTTCNR2 | |
| SCHEMBL6710237 | 0.87 | CNR2 (0.42) | HIF1ANPSR1RXFP1ALDH1A1TSHR | |
| SCHEMBL6710425 | 0.87 | HDAC3 (0.43) | HIF1ANPSR1RXFP1ALDH1A1TSHR | |
| SCHEMBL6707742 | 0.87 | ROCK1 (0.47) | HIF1ANPSR1RXFP1F10ROCK1 | |
| SCHEMBL6707713 | 0.86 | HIF1A (0.41) | HIF1ANPSR1RXFP1F10GPR35 | |
| SCHEMBL6708225 | 0.86 | CNR2 (0.46) | HIF1ANPSR1RXFP1ALDH1A1TSHR | |
| SCHEMBL6709962 | 0.86 | RXFP1 (0.37) | HIF1ANPSR1RXFP1F10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885NPSR1 2999/4885RXFP1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.