Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.74 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218014 | 1.00 | NCOA1 (0.74) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL13779312 | 0.85 | NCOA1 (1.00) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL12807528 | 0.83 | MEN1 (0.72) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL20982002 | 0.83 | KMT2A (1.00) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL20982004 | 0.83 | GAA (0.76) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL15742301 | 0.83 | KMT2A (1.00) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL18591317 | 0.83 | GAA (0.76) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL19425616 | 0.81 | NCOA1 (0.69) | NCOA1NCOA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL6714010 | 0.78 | MAPT (0.67) | KMT2AMEN1HSP90AA1SMN1; SMN2LMNA | |
| SCHEMBL12807532 | 0.78 | KMT2A (0.69) | NCOA1NCOA3KMT2AMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | ALMSTEAD JI-IN KIM (US) | 2004-03-18 | — | — | US | claimed |
| US-6660737-B2 | Antihypoxic agents | THE PROCTER & GAMBLE COMPANY | 2003-12-09 | — | — | US | claimed |
| US-20030092716-A1 | Medicinal uses of hydrazones | THE PROCTER & GAMBLE COMPANY | 2003-05-15 | — | — | US | claimed |
| US-20040053977-A1 | Medicinal uses of hydrazones | ALMSTEAD JI-IN KIM (US) | 2004-03-18 | — | — | US | disclosed |
| US-6660737-B2 | Antihypoxic agents | THE PROCTER & GAMBLE COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030092716-A1 | Medicinal uses of hydrazones | THE PROCTER & GAMBLE COMPANY | 2003-05-15 | — | — | US | disclosed |
| WO-2002089809-A1 | MEDICINAL USES OF HYDRAZONES AND HYDRAZINES | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | PGF, VEGFA, TEK | NCOA1 2533/4885NCOA3 3350/4885KMT2A 3683/4885 |
| US-20030092716-A1 | Medicinal uses of hydrazones | EPOR, VEGFA, HIF1A | NCOA1 2149/4885NCOA3 3268/4885KMT2A 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.