Sugi Predict

Sugi Predict / Compounds / SCHEMBL6712868

SCHEMBL6712868

SCHEMBL6712868

COc1cc(CN(CCN(Cc2cc(OC)c(OC)c(OC)c2)Cc2ccccn2)Cc2ccccn2)cc(OC)c1OC

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ MAPT P10636 3/20 0.59
▸ TDP1 Q9NUW8 3/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ LIN28A Q9H9Z2 1/20 0.59
▸ TP53 P04637 3/20 0.51
▸ POLB P06746 2/20 0.48
▸ PDE4A P27815 1/20 0.47
▸ PDE4B Q07343 1/20 0.47
▸ PDE4C Q08493 1/20 0.47
▸ PDE4D Q08499 1/20 0.47
▸ LMNA P02545 1/20 0.45
▸ THRB P10828 1/20 0.45
▸ PKM P14618 1/20 0.45
▸ KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16626917 0.78 HSP90AB1 (0.51) KDM4EALDH1A1SMN1; SMN2TP53POLB
SCHEMBL20393662 0.78 ALDH1A1 (0.50) KDM4EALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL12977579 0.77 TSHR (0.55) KDM4EALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL15810346 0.77 MAPT (0.53) KDM4EALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL231092 0.77 TDP1 (1.00) KDM4EALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL29427509 0.77 TDP1 (1.00) KDM4EALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL15271054 0.76 SMN1; SMN2 (0.57) KDM4EALDH1A1SMN1; SMN2TP53POLB
SCHEMBL5562538 0.76 SMN1; SMN2 (0.81) KDM4EALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL10609540 0.75 TDP1 (0.96) KDM4EALDH1A1MAPTTDP1SMN1; SMN2
SCHEMBL20393581 0.75 SMN1; SMN2 (0.51) KDM4EALDH1A1SMN1; SMN2TP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040152735-A1 NO-synthase inhibitors comprising N,N'-bis(2-pyridyl)methyl-N,N'-bis(3,4,5-trimethoxybenzyl) ethylenediamine SOCIETE L'OREAL, S.A. (FR) 2004-08-05 — — US claimed
EP-0755925-B1 N,N'-di(aralkyl)-N,N'-di(2-azaaralkyl)alkylene-diamine derivatives and their use in pharmaceutical and cosmetic compositions OREAL (FR) 1998-11-11 — — EP claimed
US-5760037-A SKIN AGING, RADIATION AND OXIDATION RESISTANCE; FREE RADICALSCAVENGERS L'OREAL (FR) 1998-06-02 — — US claimed
EP-0755925-A1 N,N'-di(aralkyl)-N,N'-di(2-azaaralkyl)alkylene-diamine derivatives and their use in pharmaceutical and cosmetic compositions L'OREAL (FR) 1997-01-29 — — EP claimed
US-20040152735-A1 NO-synthase inhibitors comprising N,N'-bis(2-pyridyl)methyl-N,N'-bis(3,4,5-trimethoxybenzyl) ethylenediamine SOCIETE L'OREAL, S.A. (FR) 2004-08-05 — — US disclosed
US-20040152735-A1 NO-synthase inhibitors comprising N,N'-bis(2-pyridyl)methyl-N,N'-bis(3,4,5-trimethoxybenzyl) ethylenediamine SOCIETE L'OREAL, S.A. (FR) 2004-08-05 — — US disclosed
US-20040152735-A1 NO-synthase inhibitors comprising N,N'-bis(2-pyridyl)methyl-N,N'-bis(3,4,5-trimethoxybenzyl) ethylenediamine SOCIETE L'OREAL, S.A. (FR) 2004-08-05 — — US disclosed
EP-0755925-B1 N,N'-di(aralkyl)-N,N'-di(2-azaaralkyl)alkylene-diamine derivatives and their use in pharmaceutical and cosmetic compositions OREAL (FR) 1998-11-11 — — EP disclosed
US-5786410-A Polyurethane dye based inks XEROX CORPORATION (US) 1998-07-28 — — US disclosed
US-5760037-A SKIN AGING, RADIATION AND OXIDATION RESISTANCE; FREE RADICALSCAVENGERS L'OREAL (FR) 1998-06-02 — — US disclosed
EP-0755925-A1 N,N'-di(aralkyl)-N,N'-di(2-azaaralkyl)alkylene-diamine derivatives and their use in pharmaceutical and cosmetic compositions L'OREAL (FR) 1997-01-29 — — EP disclosed