SCHEMBL231092

SCHEMBL231092

c1ccc(CN(CCN(Cc2ccccn2)Cc2ccccn2)Cc2ccccn2)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 1.00
MAPT P10636 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
LIN28A Q9H9Z2 1/20 1.00
KCNA5 P22460 1/20 0.52
KMT2A Q03164 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
HRH1 P35367 1/20 0.48
TERT O14746 1/20 0.47
ALDH1A1 P00352 1/20 0.46
KDM4E B2RXH2 2/20 0.45
TSHR P16473 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
POLB P06746 1/20 0.45
HRH3 Q9Y5N1 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CXCR4 P61073 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427509 1.00 TDP1 (1.00) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL10609540 0.98 TDP1 (0.96) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL6864020 0.92 MAPT (0.85) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL7107996 0.91 MAPT (0.84) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL138261 0.91 SMN1; SMN2 (0.83) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL6864949 0.90 TDP1 (0.81) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL343596 0.90 SMN1; SMN2 (0.81) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL5562538 0.90 SMN1; SMN2 (0.81) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL8772399 0.90 TDP1 (0.81) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL23642699 0.89 TDP1 (0.79) TDP1MAPTSMN1; SMN2LIN28AKCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2034 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741492-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2026-05-13 EP claimed
US-12558409-B2 Streptococcal vaccine formulations and uses thereof GPN Vaccines Ltd (AU) 2026-02-24 US claimed
US-20260028685-A1 Saliva Stabilization Solution For Use In Nucleic Acid Amplification Reactions And Methods Of Use For The Detection Of Pathogen Nucleic Acids UNIV COLORADO REGENTS (US) 2026-01-29 US claimed
EP-4648769-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2025-11-19 EP claimed
US-12398389-B2 Methods for isolating nucleic acids with size selection NATERA, INC. (US) 2025-08-26 US claimed
EP-4028494-B1 REDUCING FRICTION IN COMBUSTION ENGINES THROUGH FUEL ADDITIVES CHEVRON ORONITE CO (US) 2025-08-06 EP claimed
CN-115857351-B Solid oxide fuel cell system model and testing method 华中科技大学 2025-05-30 CN claimed
US-20250161186-A1 LIQUID BOTULINUM TOXIN FORMULATION AND USE THEREOF MERZ PHARMA GMBH & CO. KGAA (DE) 2025-05-22 US claimed
US-20250152682-A1 LIQUID BOTULINUM TOXIN FORMULATION AND USE THEREOF MERZ PHARMA GMBH & CO. KGAA (DE) 2025-05-15 US claimed
EP-3042645-B2 Dental composites with improved storage stability IVOCLAR VIVADENT AG (LI) 2025-03-12 EP claimed
US-20030203973-A1 Preventing and/or treating cardiovascular disease and/or associated heart failure PHILERA NEW ZEALAND LIMITED (NZ) 2003-10-30 US claimed
WO-2003087079-A1 CONVERSION OF TAXANE MOLECULES NATURAL PHARMACEUTICALS, INC. (US) 2003-10-23 WO claimed
EP-0740528-B1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX THERAPEUTICS INC (US) 2003-03-26 EP claimed
US-6231852-B1 Method for reducing BCL-2 expressing cells resistance to death THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-05-15 US claimed
US-6022490-A FOR ACTIVATING PEROXY BLEACH LEVER BROTHERS COMPANY (US) 2000-02-08 US claimed
EP-0740528-A4 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP (US) 1998-04-01 EP claimed
US-5733572-A Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles IMARX PHARMACEUTICAL CORP. (US) 1998-03-31 US claimed
WO-1997009976-A2 METHOD OF REDUCING NEUROTOXIC INJURY WITH ZINC CHELATORS WASHINGTON UNIVERSITY (CH) 1997-03-20 WO claimed
EP-0740528-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1996-11-06 EP claimed
WO-1995015118-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1995-06-08 WO claimed