Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PCK1 | P35558 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031128 | 0.88 | LMNA (0.52) | SIGMAR1LMNAKDM4EPOLBTSHR | |
| SCHEMBL4025307 | 0.88 | LMNA (0.52) | SIGMAR1LMNAKDM4EPOLBTSHR | |
| SCHEMBL4031595 | 0.88 | LMNA (0.52) | SIGMAR1LMNAKDM4EPOLBTSHR | |
| SCHEMBL4025289 | 0.87 | DRD4 (0.46) | SIGMAR1LMNAKDM4EPOLBTSHR | |
| SCHEMBL5832664 | 0.86 | CCR3 (0.41) | SIGMAR1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL4024063 | 0.85 | SIGMAR1 (0.45) | SIGMAR1LMNAKDM4EPOLBTSHR | |
| SCHEMBL5832660 | 0.82 | CCR3 (0.56) | SIGMAR1LMNATSHRSMN1; SMN2HTR4 | |
| SCHEMBL5843280 | 0.82 | DRD4 (0.47) | SIGMAR1LMNATSHRSMN1; SMN2HTR4 | |
| SCHEMBL2858926 | 0.81 | DRD4 (0.47) | SIGMAR1LMNAPOLBKMT2ADRD4 | |
| SCHEMBL5831904 | 0.81 | DRD4 (0.47) | SIGMAR1LMNAPOLBKMT2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058923-A1 | Morpholin-acetamide derivatives for the treatment of inflammatory diseases | SMITHKLINE BEECHAM CORPORATION | 2004-03-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058923-A1 | Morpholin-acetamide derivatives for the treatment of inflammatory diseases | CCR1, MALT1, REL | SIGMAR1 99/4885LMNA 1238/4885KDM4E 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.