Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520789 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL27791455 | 0.79 | CDC7 (0.50) | ALDH1A1KDM4EADORA2AADORA1NLRP3 | |
| SCHEMBL6715377 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL6085101 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL23697527 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL199306 | 0.77 | ALDH1A1 (0.65) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL28812535 | 0.75 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL31519065 | 0.75 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL28222796 | 0.75 | KDM4E (0.44) | ALDH1A1KDM4ELMNAMAPK1NPC1 | |
| SCHEMBL28326781 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102465-A1 | Pyrazolyl pyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-05-27 | — | — | US | disclosed |
| EP-1363905-A1 | PYRAZOLYL PYRIMIDINES | Bayer CropScience AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002068413-A1 | PYRAZOLYL PYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102465-A1 | Pyrazolyl pyrimidines | ZYX, P2RX5, P2RX1 | ALDH1A1 1322/4885KDM4E 3833/4885LMNA 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.