Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14140173 | 1.00 | DRD2 (0.43) | DRD2DRD3TAAR1MMEMEN1 | |
| SCHEMBL18638022 | 0.82 | DRD2 (0.42) | DRD2DRD3TAAR1MMEMEN1 | |
| SCHEMBL22604467 | 0.82 | DRD2 (0.42) | DRD2DRD3TAAR1MMEMEN1 | |
| SCHEMBL13634509 | 0.81 | DRD2 (0.44) | DRD2DRD3TAAR1MMEMEN1 | |
| SCHEMBL680803 | 0.80 | — | — | |
| SCHEMBL8025772 | 0.80 | DRD2 (0.49) | DRD2DRD3TAAR1MMEMEN1 | |
| SCHEMBL8025775 | 0.80 | DRD2 (0.49) | DRD2DRD3TAAR1MMEMEN1 | |
| SCHEMBL15698411 | 0.79 | TAAR1 (0.42) | DRD2DRD3TAAR1MMEMEN1 | |
| SCHEMBL16185939 | 0.78 | DRD2 (0.40) | DRD2DRD3TAAR1MME | |
| SCHEMBL6250063 | 0.78 | DRD2 (0.40) | DRD2DRD3TAAR1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101234329-A | SiO2 granule surface molecule print adsorption agent and preparation thereof | UNIV HUAZHONG SCIENCE TECH (CN) | 2008-08-06 | — | — | CN | claimed |
| CN-100404127-C | Artificial anitibody type composite photocatalyst and its prepn. method | UNIV HUAZHONG SCIENCE TECH (CN) | 2008-07-23 | — | — | CN | claimed |
| CN-1868580-A | Artificial anitibody type composite photocatalyst and its prepn. method | UNIV HUAZHONG SCIENCE TECH (CN) | 2006-11-29 | — | — | CN | claimed |
| US-20170152242-A1 | PYRAZINE DERIVATIVES | TEIJIN PHARMA LIMITED (JP) | 2017-06-01 | — | — | US | disclosed |
| CN-101234329-A | SiO2 granule surface molecule print adsorption agent and preparation thereof | UNIV HUAZHONG SCIENCE TECH (CN) | 2008-08-06 | — | — | CN | disclosed |
| CN-100404127-C | Artificial anitibody type composite photocatalyst and its prepn. method | UNIV HUAZHONG SCIENCE TECH (CN) | 2008-07-23 | — | — | CN | disclosed |
| CN-1868580-A | Artificial anitibody type composite photocatalyst and its prepn. method | UNIV HUAZHONG SCIENCE TECH (CN) | 2006-11-29 | — | — | CN | disclosed |
| US-20040096664-A1 | Optically active polythiophene aggregate and its preparation | NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152242-A1 | PYRAZINE DERIVATIVES | XDH, SLC5A2, SLC5A1 | DRD2 4664/4885DRD3 4495/4885TAAR1 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.