Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.46 |
| ▸ | PPARA | Q07869 | 17/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713518 | 0.85 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL5633796 | 0.83 | HDAC1 (0.42) | PPARGPPARA | |
| SCHEMBL5633799 | 0.83 | HDAC1 (0.42) | PPARGPPARA | |
| SCHEMBL6716386 | 0.82 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL6713079 | 0.81 | PPARG (0.43) | PPARGPPARAL3MBTL1 | |
| SCHEMBL6557624 | 0.76 | PPARG (0.54) | PPARGPPARALMNAL3MBTL1 | |
| SCHEMBL6716134 | 0.75 | PPARA (0.74) | PPARGPPARALMNAL3MBTL1 | |
| SCHEMBL6714818 | 0.74 | PPARG (0.55) | PPARGPPARALMNAL3MBTL1 | |
| SCHEMBL9953340 | 0.74 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL767041 | 0.74 | TDP1 (0.55) | PPARGPPARALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| CN-1280561-A | Amidocarboxylic acid derivatives | SANKYO CO (JP) | 2001-01-17 | — | — | CN | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | PPARG 23/4885PPARA 71/4885LMNA 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.