Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719501 | 0.89 | MAPT (0.46) | TP53CYP2C9MEN1KMT2AMAPT | |
| SCHEMBL6716842 | 0.84 | CYP1A2 (0.48) | CYP2C9MAPTCYP2D6CYP2C19NPSR1 | |
| SCHEMBL6716835 | 0.84 | CYP1A2 (0.48) | CYP2C9MAPTCYP2D6CYP2C19NPSR1 | |
| SCHEMBL6715819 | 0.81 | POLB (0.49) | CYP2C9MEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL6717632 | 0.81 | ATM (0.47) | CYP2C9MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL6716822 | 0.81 | KCNQ2 (0.56) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL6723623 | 0.80 | POLB (0.51) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL6715907 | 0.80 | KMT2A (0.50) | MDM4TP53MEN1KMT2AMAPT | |
| SCHEMBL6719510 | 0.79 | MAPT (0.55) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6716854 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | SLC1A2, SLC6A7, SLC1A1 | MDM4 4427/4885TP53 4017/4885CYP2C9 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.