Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 16/20 | 0.55 |
| ▸ | METTL14 | Q9HCE5 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716035 | 1.00 | METTL3 (0.55) | METTL3METTL14KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL30433176 | 0.81 | METTL3 (0.49) | METTL3METTL14KDM4ERXFP1ADORA3 | |
| SCHEMBL30433464 | 0.79 | METTL3 (0.50) | METTL3KDM4ERXFP1ADORA3ADORA2A | |
| SCHEMBL5634687 | 0.75 | KCNH2 (0.63) | METTL3RXFP1MAPT | |
| SCHEMBL30432768 | 0.73 | METTL3 (0.50) | METTL3METTL14 | |
| SCHEMBL30132372 | 0.72 | PKM (0.57) | METTL3KDM4ESMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL22499218 | 0.72 | METTL3 (1.00) | METTL3 | |
| SCHEMBL15575017 | 0.71 | KDM4E (0.51) | METTL3KDM4ESMN1; SMN2ALDH1A1RXFP1 | |
| SCHEMBL30433263 | 0.70 | METTL3 (0.56) | METTL3METTL14KDM4EALDH1A1 | |
| SCHEMBL30433547 | 0.70 | METTL3 (0.57) | METTL3METTL14KDM4EADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171620-A1 | Nitrogen-containing bicyclic heterocycles for use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2004-09-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171620-A1 | Nitrogen-containing bicyclic heterocycles for use as antibacterials | NRDC, NUCB2, NDC1 | METTL3 2929/4885METTL14 2417/4885KDM4E 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.