SCHEMBL6716191

SCHEMBL6716191

CCN(OC)c1nc(N)nc(N(CC)OC)n1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
PTPRF P10586 1/20 0.32
PTPN1 P18031 1/20 0.32
PTPRA P18433 1/20 0.32
PTPN11 Q06124 1/20 0.32
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNE1 P24864 1/20 0.31
CDK2 P24941 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NOS1 P29475 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27491512 0.96 MAPT (0.37) MAPTKMT2AKDM4EPTPRFPTPN1
SCHEMBL6716050 0.80 DHFR (0.34) MAPTKMT2ACDK1CCNB1CDK2
SCHEMBL29680078 0.77 MAPT (0.36) MAPTKMT2AKDM4EPTPRFPTPN1
SCHEMBL1068958 0.77 NPC1 (0.33) LMNANPC1
SCHEMBL6720140 0.76 DHFR (0.34) MAPTKMT2ACDK1CCNB1CDK2
SCHEMBL3732345 0.75
SCHEMBL7526488 0.75 MAPT (0.36) MAPTKMT2AMEN1LMNAL3MBTL1
SCHEMBL7096975 0.73 MEN1 (0.32) KMT2AMEN1LMNAL3MBTL1
SCHEMBL1101401 0.72
SCHEMBL29231394 0.72 MAPT (0.33) MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040200993-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2004-10-14 US claimed
US-20030168629-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2003-09-11 US claimed
US-20040200993-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2004-10-14 US disclosed
US-20030168629-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2003-09-11 US disclosed
WO-2003050094-A1 REACTIVE LIQUID POLYMER CROSSLINKING AGENT AND PROCESS FOR PREPARATION LCB WORLDWIDE INC. (US) 2003-06-19 WO disclosed