SCHEMBL6720140

SCHEMBL6720140

CCCCN(OC)c1nc(N)nc(N)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.34
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TLR8 Q9NR97 6/20 0.32
TLR7 Q9NYK1 4/20 0.32
HRH2 P25021 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
CRHR1 P34998 1/20 0.30
CDK1 P06493 1/20 0.30
CCNB1 P14635 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
CCNA1 P78396 1/20 0.30
PIN1 Q13526 1/20 0.30
CASP1 P29466 1/20 0.30
MAPT P10636 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6716050 0.96 DHFR (0.34) DHFRLMNAMEN1KMT2AL3MBTL1
SCHEMBL7096975 0.87 MEN1 (0.32) DHFRLMNAMEN1KMT2AL3MBTL1
SCHEMBL27491512 0.80 MAPT (0.37) LMNAMEN1KMT2AL3MBTL1SMN1; SMN2
SCHEMBL27729331 0.80 LMNA (0.35) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL6716191 0.76 MAPT (0.41) LMNAMEN1KMT2AL3MBTL1CDK1
SCHEMBL1032549 0.76 SLC29A1 (0.41) DHFRLMNAMEN1KMT2AL3MBTL1
SCHEMBL1068958 0.75 NPC1 (0.33) LMNA
SCHEMBL4419657 0.75 PTPN11 (0.39) DHFRLMNAPKMSMN1; SMN2TLR8
SCHEMBL27941262 0.73 DHFR (0.35) DHFRLMNAMEN1KMT2AL3MBTL1
SCHEMBL9613748 0.73 LMNA (0.35) LMNAPKMSMN1; SMN2TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040200993-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2004-10-14 US claimed
US-20030168629-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2003-09-11 US claimed
US-20040200993-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2004-10-14 US disclosed
US-20030168629-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2003-09-11 US disclosed
WO-2003050094-A1 REACTIVE LIQUID POLYMER CROSSLINKING AGENT AND PROCESS FOR PREPARATION LCB WORLDWIDE INC. (US) 2003-06-19 WO disclosed