Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PNLIP | P16233 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15361447 | 0.81 | PTGS1 (0.68) | TDP1MAPTABL1EPHX2TRPV1 | |
| SCHEMBL6713049 | 0.81 | TDP1 (0.58) | TDP1MAPTPTGS2ABL1EPHX2 | |
| SCHEMBL15229156 | 0.79 | SMO (0.59) | TDP1MAPTMEN1KMT2AHTT | |
| SCHEMBL6683080 | 0.79 | TDP1 (0.56) | TDP1MAPTPTGS2ABL1EPHX2 | |
| SCHEMBL27940176 | 0.79 | EPHX2 (0.58) | TDP1MAPTABL1EPHX2TRPV1 | |
| SCHEMBL15361780 | 0.78 | NPC1 (0.58) | TDP1MAPTMEN1KMT2ASMN1; SMN2 | |
| Triflumuron SCHEMBL9490691 | 0.77 | TDP1 (1.00) | TDP1MAPTEPHX2MEN1KMT2A | |
| Triflumuron SCHEMBL29832813 | 0.77 | TDP1 (1.00) | TDP1MAPTEPHX2MEN1KMT2A | |
| Triflumuron SCHEMBL23700 | 0.77 | TDP1 (1.00) | TDP1MAPTEPHX2MEN1KMT2A | |
| SCHEMBL1499586 | 0.77 | MAPT (0.61) | TDP1MAPTABL1EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | DDT, NRDC, NOXO1 | TDP1 2624/4885MAPT 4447/4885PTGS2 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.