Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683082 | 0.83 | TDP1 (0.50) | TDP1MAPTPTGS2ABL1TRPV1 | |
| SCHEMBL171565 | 0.79 | EPHX2 (0.67) | MAPTTRPV1MEN1KMT2AEPHX2 | |
| SCHEMBL6716560 | 0.79 | TDP1 (0.62) | TDP1MAPTPTGS2ABL1TRPV1 | |
| SCHEMBL6713049 | 0.75 | TDP1 (0.58) | TDP1MAPTPTGS2ABL1TRPV1 | |
| SCHEMBL1496356 | 0.73 | TRPV1 (0.59) | TDP1MAPTABL1TRPV1NPC1 | |
| SCHEMBL12225782 | 0.73 | NPC1 (0.69) | TDP1MAPTTRPV1MEN1KMT2A | |
| SCHEMBL18855245 | 0.72 | PTGS2 (0.52) | TDP1MAPTPTGS2TRPV1MEN1 | |
| SCHEMBL5176800 | 0.72 | TSHR (0.49) | MAPTPTGS2MEN1KMT2ANPC1 | |
| SCHEMBL4423725 | 0.72 | ALDH1A1 (0.52) | TDP1MAPTPTGS2ABL1TRPV1 | |
| SCHEMBL24823651 | 0.72 | ABL1 (0.47) | TDP1MAPTABL1TRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-11-25 | — | — | US | disclosed |
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | DDT, NRDC, NOXO1 | TDP1 2624/4885MAPT 4447/4885PTGS2 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.