SCHEMBL6716581

SCHEMBL6716581

CCC(O)CCCCC(O)CC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.42
TSHR P16473 2/20 0.41
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 1/20 0.41
NFKB1 P19838 1/20 0.39
ACACB O00763 1/20 0.36
ACACA Q13085 1/20 0.36
PSMD14 O00487 2/20 0.35
PLA2G1B P04054 2/20 0.35
MMP2 P08253 2/20 0.35
ATG4B Q9Y4P1 2/20 0.35
HSP90AA1 P07900 1/20 0.35
RAD52 P43351 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
TRPA1 O75762 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28576044 1.00 GPR84 (0.42) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL28578505 1.00 GPR84 (0.42) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL30787291 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL30787116 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL30787307 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL23530055 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL30787428 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL30787207 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL14660129 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1
SCHEMBL2845646 0.97 GPR84 (0.46) GPR84TSHRFFAR1FFAR4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116135866-A Bridged carboxylic acid-containing difunctional phosphine ligand, preparation method and application thereof 中山大学 2023-05-19 CN claimed
CN-109336887-B Benzimidazole chiral heterocyclic compound and preparation method and application thereof 中山大学 2021-12-17 CN claimed
CN-106831862-B Chiral bridged axial chiral monophosphine ligand and preparation method thereof 中山大学 2021-01-15 CN claimed
CN-116135866-A Bridged carboxylic acid-containing difunctional phosphine ligand, preparation method and application thereof 中山大学 2023-05-19 CN disclosed
CN-109336887-B Benzimidazole chiral heterocyclic compound and preparation method and application thereof 中山大学 2021-12-17 CN disclosed
CN-106831862-B Chiral bridged axial chiral monophosphine ligand and preparation method thereof 中山大学 2021-01-15 CN disclosed
EP-2700636-B1 PROCESS FOR PREPARING EPISULFIDE COMPOUNDS ASAHI CHEMICAL IND (JP) 2017-08-02 EP disclosed
CN-106831862-A Axial chirality monophosphorus ligand of one class chirality bridging and preparation method thereof 中山大学 2017-06-13 CN disclosed
US-9359324-B2 Process for preparing episulfide compounds ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-06-07 US disclosed
US-20150197501-A1 Process for Preparing Episulfide Compounds ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-07-16 US disclosed
US-9051293-B2 Process for preparing episulfide compounds ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-06-09 US disclosed
CN-104610222-A Process for preparing episulfide compounds ASAHI KASEI CHEMICALS CORP 2015-05-13 CN disclosed
US-20140107350-A1 Process for Preparing Episulfide Compounds ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-04-17 US disclosed
EP-2700636-A1 PROCESS FOR PREPARING EPISULFIDE COMPOUNDS Asahi Kasei Chemicals Corporation (JP) 2014-02-26 EP disclosed
US-6799845-B2 INK JET INK, PERMEABILITY AND DRYING PROPERTIES RICOH COMPANY, LTD. (JP) 2004-10-05 US disclosed
EP-1213331-B1 Recording liquid, recording cartridge, recording method, recording apparatus and recording medium RICOH KK (JP) 2004-04-28 EP disclosed
US-20030079647-A1 Recording liquid, recording cartridge, recording method, recording apparatus and recording medium RICOH COMPANY, LTD. (JP) 2003-05-01 US disclosed
EP-1213331-A1 Recording liquid, recording cartridge, recording method, recording apparatus and recording medium Ricoh Company, Ltd. (JP) 2002-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150197501-A1 Process for Preparing Episulfide Compounds TST, EPHX2, STS GPR84 3934/4885TSHR 1233/4885FFAR1 4701/4885
US-20140107350-A1 Process for Preparing Episulfide Compounds TST, EPHX2, STS GPR84 3934/4885TSHR 1233/4885FFAR1 4701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.