Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859017 | 0.97 | ALDH1A1 (0.30) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL25324988 | 0.86 | — | — | |
| SCHEMBL1536734 | 0.73 | — | — | |
| SCHEMBL2275108 | 0.73 | TDP1 (0.30) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL29211176 | 0.73 | ATM (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL6511720 | 0.71 | ATM (0.37) | ALDH1A1MAPK1 | |
| SCHEMBL28018162 | 0.71 | — | — | |
| SCHEMBL10720345 | 0.71 | — | — | |
| SCHEMBL5339519 | 0.71 | — | — | |
| SCHEMBL27353113 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431990-B | Preparation method of N- (4-ethoxycarbonylphenyl) -N '-methyl-N' -phenylformamidine | 中昊(大连)化工研究设计院有限公司 | 2018-09-07 | — | — | CN | disclosed |
| EP-1083903-B1 | BRIDGED INDENOPYRROLOCARBAZOLES | CEPHALON INC (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6359130-B1 | ANTIBIOTIC, ANTITUMOR AGENT, ANTIINFLAMMATORY AGENT | CEPHALON, INC. | 2002-03-19 | — | — | US | disclosed |
| EP-1083903-A4 | BRIDGED INDENOPYRROLOCARBAZOLES | CEPHALON INC (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1083903-A1 | BRIDGED INDENOPYRROLOCARBAZOLES | CEPHALON, INC. (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6127401-A | TREATMENT OF PROSTATE DISORDERS, ANGIOGENIC DISORDERS, NEOPLASIA, RHEUMATOID ARTHRITIS, PULMONARY FIBROSIS, MYELOFIBROSIS, ABNORMAL WOUND HEALING, ATHEROSCLEROSIS, OR RESTENOSIS, ALZHEIMER'S DISEASE | CEPHALON, INC. (US) | 2000-10-03 | — | — | US | disclosed |
| WO-1999062523-A1 | BRIDGED INDENOPYRROLOCARBAZOLES | CEPHALON, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0148636-B1 | IMPROVED SURFACE COATING COMPOSITIONS | ALCAN INTERNATIONAL LIMITED (CA) | 1986-11-26 | — | — | EP | disclosed |
| EP-0148636-A2 | Improved surface coating compositions | ALCAN INTERNATIONAL LIMITED (CA) | 1985-07-17 | — | — | EP | disclosed |
| US-4090886-A | STORAGE STABILITY, ALUMINUM ALKOXIDE WITH ALKANOL, ALKOXYALKANOL, KETO ESTER, WATER, HYDROGEN PEROXIDE, ORGANIC HYDROPEROXIDE OR MIXTURES | MANCHEM LIMITED (EN) | 1978-05-23 | — | — | US | disclosed |