Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL6710093 | 0.97 | KAT6A (0.41) | KAT6AGPR174ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8371253 | 0.97 | KAT6A (0.41) | KAT6AGPR174ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6716898 | 0.97 | KAT6A (0.41) | KAT6AGPR174ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6713982 | 0.97 | KAT6A (0.41) | KAT6AGPR174ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8372476 | 0.85 | ALDH1A1 (0.42) | KAT6AGPR174ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6712693 | 0.83 | GPR174 (0.48) | KAT6AGPR174ALDH1A1LMNAMEN1 | |
| SCHEMBL6714658 | 0.80 | GPR174 (0.48) | KAT6AGPR174ALDH1A1LMNAMEN1 | |
| Potassium Ion SCHEMBL6710228 | 0.80 | GPR174 (0.48) | KAT6AGPR174ALDH1A1LMNAMEN1 | |
| SCHEMBL1129346 | 0.80 | GPR174 (0.48) | KAT6AGPR174ALDH1A1LMNAMEN1 | |
| SCHEMBL6710230 | 0.80 | GPR174 (0.48) | KAT6AGPR174ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740722-B2 | Low density acrylic fiber | SOLUTIA INC. | 2004-05-25 | — | — | US | disclosed |
| US-20030057593-A1 | Low density acrylic fiber | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC | 2003-03-27 | — | — | US | disclosed |