Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 4/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671108 | 0.88 | HSD11B1 (0.40) | HSD11B1CYP3A4P2RX7PGRNR3C2 | |
| SCHEMBL672551 | 0.87 | HSD11B1 (0.39) | HSD11B1CYP3A4P2RX7PGRNR3C2 | |
| SCHEMBL170324 | 0.87 | HSD11B1 (0.39) | HSD11B1CYP3A4P2RX7PGRNR3C2 | |
| SCHEMBL1726063 | 0.82 | HSD11B1 (0.40) | HSD11B1CYP3A4P2RX7PTPN11PDE2A | |
| SCHEMBL1725413 | 0.80 | HSD11B1 (0.39) | HSD11B1CYP3A4P2RX7PGRNR3C2 | |
| SCHEMBL173227 | 0.78 | HSD11B1 (0.38) | HSD11B1CYP3A4P2RX7PTPN11PDE2A | |
| SCHEMBL1725409 | 0.78 | HSD11B1 (0.39) | HSD11B1CYP3A4P2RX7PGRNR3C2 | |
| SCHEMBL173619 | 0.77 | HSD11B1 (0.47) | HSD11B1CYP3A4P2RX7PTPN11PDE2A | |
| SCHEMBL29520229 | 0.77 | HSD11B1 (0.47) | HSD11B1CYP3A4P2RX7PTPN11PDE2A | |
| SCHEMBL20698175 | 0.76 | HSD11B1 (0.49) | HSD11B1P2RX7PTPN11PDE2APDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123323-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-16 | — | — | US | claimed |
| WO-2012023143-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | claimed |
| WO-2012024586-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | claimed |
| US-20130123323-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-16 | — | — | US | disclosed |
| WO-2012023143-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012024586-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123323-A1 | FUNGICIDAL PYRAZOLES | CBR3, CYP1A1, CYP1B1 | HSD11B1 788/4885CYP3A4 9/4885P2RX7 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.