SCHEMBL173619

SCHEMBL173619

Cc1nn(C)c(N)c1-c1ccc(F)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.47
MAPT P10636 1/20 0.46
MAPK14 Q16539 1/20 0.40
PTPN11 Q06124 1/20 0.39
SCN10A Q9Y5Y9 1/20 0.39
P2RX7 Q99572 1/20 0.39
PDE2A O00408 2/20 0.37
PDE10A Q9Y233 2/20 0.37
PDE7A Q13946 1/20 0.37
ALK Q9UM73 3/20 0.36
PDE6D O43924 1/20 0.36
PDE6A P16499 1/20 0.36
PDE6G P18545 1/20 0.36
PDE6B P35913 1/20 0.36
PDE6C P51160 1/20 0.36
PDE6H Q13956 1/20 0.36
KMT2A Q03164 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
CYP3A4 P08684 1/20 0.36
DPP4 P27487 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520229 1.00 HSD11B1 (0.47) HSD11B1MAPTMAPK14PTPN11SCN10A
SCHEMBL20698175 0.85 HSD11B1 (0.49) HSD11B1PTPN11P2RX7PDE2APDE10A
SCHEMBL1725607 0.85 MAPT (0.49) MAPTMAPK14ALKKMT2ADPP4
SCHEMBL20698256 0.85 MAPT (0.49) HSD11B1MAPTPDE2AKMT2ACYP3A4
SCHEMBL171101 0.82 HSD11B1 (0.47) HSD11B1MAPK14PTPN11SCN10AP2RX7
SCHEMBL17514923 0.82 HSD11B1 (0.47) HSD11B1PTPN11SCN10AP2RX7PDE2A
SCHEMBL30415275 0.82 MAPT (0.46) HSD11B1MAPTMAPK14ALKKMT2A
SCHEMBL20698132 0.82 HPGD (0.50) HSD11B1PTPN11SCN10AP2RX7PDE2A
SCHEMBL20698133 0.82 POLB (0.52) HSD11B1MAPTMAPK14SCN10AP2RX7
SCHEMBL20698134 0.82 HSD11B1 (0.41) HSD11B1MAPTMAPK14PTPN11SCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4167740-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-26 EP claimed
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles FMC CORPORATION (US) 2025-08-26 US disclosed
EP-4388876-A2 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC Corporation (US) 2024-06-26 EP disclosed
CN-112969688-B Fungicidal nitroaniline-substituted pyrazoles FMC公司 2024-06-04 CN disclosed
EP-3847160-B1 FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES FMC CORP (US) 2024-05-08 EP disclosed
EP-3590340-B1 INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES FMC CORP (US) 2023-11-15 EP disclosed
US-20230148599-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES FMC CORPORATION 2023-05-18 US disclosed
CN-115989255-A Aqueous capsule suspension concentrate containing biodegradable ester groups 拜耳公司 2023-04-18 CN disclosed
CN-111989328-B Heterocyclic derivatives as pest control agents 拜耳公司 2023-04-18 CN disclosed
CN-115955916-A Active compound combinations 拜耳公司 2023-04-11 CN disclosed
WO-2012031061-A2 FUNGICIDAL PYRAZOLES AND THEIR MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-08 WO disclosed
WO-2012024586-A1 FUNGICIDAL PYRAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-23 WO disclosed
WO-2012023143-A1 FUNGICIDAL PYRAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-23 WO disclosed
EP-2403834-A1 Fungicidal pyrazoles E. I. du Pont de Nemours and Company (US) 2012-01-11 EP disclosed
US-20110319430-A1 FUNGICIDAL PYRAZOLES E.I. DU PONT NEMOURS AND COMPANY (US) 2011-12-29 US disclosed
US-20110045101-A1 FUNGICIDAL SUBSTITUTED AZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-24 US disclosed
EP-2274284-A2 FUNGICIDAL SUBSTITUTED AZOLES E. I. Du Pont de Nemours and Company (US) 2011-01-19 EP disclosed
WO-2010101973-A1 FUNGICIDAL PYRAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-10 WO disclosed
WO-2009137538-A2 FUNGICIDAL SUBSTITUTED AZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-12 WO disclosed
WO-2009137651-A2 FUNGICIDAL SUBSTITUTED AZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319430-A1 FUNGICIDAL PYRAZOLES CBR3, CBR1, CYP2S1 HSD11B1 962/4885MAPT 4737/4885MAPK14 2009/4885
US-20230148599-A1 FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES CYP1B1, CYP4B1, TH HSD11B1 958/4885MAPT 134/4885MAPK14 1197/4885
US-12398107-B2 Fungicidal nitroanilino substituted pyrazoles TH, NOX1, NOX3 HSD11B1 1144/4885MAPT 216/4885MAPK14 2148/4885
US-20110045101-A1 FUNGICIDAL SUBSTITUTED AZOLES CBR3, NOX3, CBR1 HSD11B1 1193/4885MAPT 4335/4885MAPK14 2980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.