Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 5/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| Hydrochloric Acid SCHEMBL7813040 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL6446624 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL13742735 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL7008426 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL8055642 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL6361850 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2TERTKDM4E | |
| SCHEMBL16972520 | 0.71 | SMN1; SMN2 (0.87) | SMN1; SMN2TERT | |
| SCHEMBL31735543 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2DAPK3PRKD3MAP4K4PRKACA | |
| SCHEMBL30237200 | 0.70 | SMN1; SMN2 (0.44) | SMN1; SMN2TERTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023290-A1 | Novel therapeutic agents that modulate enzymatic processes | THERAVANCE BIOPHARMA R&D IP, LLC | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023290-A1 | Novel therapeutic agents that modulate enzymatic processes | RNASE1, ENGASE, ENTPD5 | SMN1; SMN2 4046/4885TERT 3990/4885DAPK3 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.