Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 5/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446624 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL617 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| Hydrochloric Acid SCHEMBL7813040 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL8055642 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL6717347 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL17604333 | 0.74 | SMN1; SMN2 (0.36) | SMN1; SMN2DAPK3PRKD3MAP4K4PRKACA | |
| SCHEMBL13742735 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2TERTDAPK3PRKD3MAP4K4 | |
| SCHEMBL1862481 | 0.73 | GAA (0.37) | KDM4EUSP2HPGDHSD17B10NMT1 | |
| SCHEMBL1095 | 0.71 | PIM3 (0.49) | SMN1; SMN2DAPK3PRKD3MAP4K4PRKACA | |
| Hydrochloric Acid SCHEMBL10919018 | 0.69 | PIM3 (0.47) | SMN1; SMN2DAPK3PRKD3MAP4K4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117890459-A | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-04-16 | — | — | CN | claimed |
| CN-117890459-B | Quick screening method for illegally adding chemical drugs into foods based on MSRIT-MS/MS | 南京市食品药品监督检验院 | 2024-10-18 | — | — | CN | disclosed |
| CN-1136219-C | Pyrazolopyrimidinone derivatives for the treatment of impotence | ������ҩ��ʽ���� | 2004-01-28 | — | — | CN | disclosed |
| EP-1129093-B1 | PYRAZOLOPYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF IMPOTENCE | DONG A PHARM CO LTD (KR) | 2003-07-23 | — | — | EP | disclosed |
| US-6583147-B1 | 5-(2-ethoxy-5-(isopropylamidosulfonyl)phenyl)-1-methyl-3-propy l- 1,6-dihydro-7H-pyrazolo(4,3-d)pyrimidin-7-one; | DONG A PHARM CO., LTD. (KR) | 2003-06-24 | — | — | US | disclosed |
| CN-1325398-A | Pyrazolopyrimidinone derivatives for the treatment of impotence | DONG A PHARM CO LTD (KR) | 2001-12-05 | — | — | CN | disclosed |
| EP-1129093-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF IMPOTENCE | Dong A Pharmaceutical Co. Ltd. (KR) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027848-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF IMPOTENCE | DONG A PHARM. CO., LTD. (KR) | 2000-05-18 | — | — | WO | disclosed |