Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951367 | 0.91 | HTR1A (0.42) | PARP10PARP11CYP19A1METAP1HTR1A | |
| SCHEMBL1583277 | 0.87 | METAP1 (0.42) | PARP10PARP11CYP19A1METAP1HTR1A | |
| SCHEMBL5952174 | 0.83 | METAP1 (0.39) | PARP10PARP11CYP19A1METAP1ANPEP | |
| SCHEMBL16201909 | 0.79 | CYP19A1 (0.50) | CYP19A1CYP26A1 | |
| SCHEMBL16193647 | 0.77 | CYP19A1 (0.50) | CYP19A1CYP26A1 | |
| SCHEMBL3066323 | 0.77 | ACHE (0.64) | PARP10PARP11ANPEPIL1RNERAP2 | |
| SCHEMBL7180368 | 0.77 | PARP10 (0.44) | PARP10PARP11ANPEPIL1RNERAP2 | |
| SCHEMBL16201914 | 0.76 | CYP19A1 (0.39) | PARP10PARP11CYP19A1METAP1CYP26A1 | |
| SCHEMBL16775659 | 0.75 | CYP19A1 (0.48) | CYP19A1CYP26A1 | |
| SCHEMBL5952058 | 0.75 | ACHE (0.60) | PARP10PARP11ANPEPIL1RNERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673880-B2 | ETHYLENE (CO)POLYMERS HAVING LOW MOLECULAR WEIGHTS AND NARROW MOLECULAR WEIGHT DISTRIBUTIONS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2004-01-06 | — | — | US | disclosed |
| EP-0941997-B1 | Bridged zirconocene compounds, process for their preparation, and their use as catalyst components in the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-12-18 | — | — | EP | disclosed |
| US-20020039962-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | MONTELL TECHNOLOGY COMPANY B.V. | 2002-04-04 | — | — | US | disclosed |
| US-6306791-B2 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | BASELL TECHNOLOGY COMPANY BV (NL) | 2001-10-23 | — | — | US | disclosed |
| US-20010014751-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymeriaztion of olefins | MONTELL TECHNOLOGY COMPANY B.V. | 2001-08-16 | — | — | US | disclosed |
| US-6232484-B1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | MONTELL TECHNOLOGY B.V. (NL) | 2001-05-15 | — | — | US | disclosed |
| EP-0941997-A2 | Bridged zirconocene compounds, process for their preparation, and their use as catalyst components in the polymerization of olefins | Montell Technology Company bv (NL) | 1999-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020039962-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymerization of olefins | ZRANB2, ZKSCAN2, ZCCHC8 | PARP10 1050/4885PARP11 1443/4885CYP19A1 3278/4885 |
| US-20010014751-A1 | Bridged zirconocene compounds, process for their preparation and their use as catalyst components in the polymeriaztion of olefins | ZRANB2, ZKSCAN2, ZNF787 | PARP10 170/4885PARP11 212/4885CYP19A1 2969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.