Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270480 | 0.86 | CYP2C19 (0.38) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL1827117 | 0.81 | DAO (0.42) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL29636400 | 0.80 | KIF11 (0.39) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL1421302 | 0.79 | DAO (0.43) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL599752 | 0.79 | DAO (0.43) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL73588 | 0.79 | DAO (0.43) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL1492740 | 0.79 | DAO (0.43) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL7432298 | 0.79 | DAO (0.43) | DAOLMNACYP2C19HCAR2TSHR | |
| SCHEMBL41617 | 0.79 | DAO (0.43) | DAOLMNACYP2C19HCAR2TSHR | |
| Hydrochloric Acid SCHEMBL9402263 | 0.77 | DAO (0.42) | DAOLMNACYP2C19HCAR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | disclosed |
| EP-1405917-A2 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | Bayer Chemicals AG (DE) | 2004-04-07 | — | — | EP | disclosed |