SCHEMBL7270480

SCHEMBL7270480

C=CC(C)(C(=O)O)c1cccs1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.38
DAO P14920 1/20 0.37
LMNA P02545 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
TSHR P16473 1/20 0.35
RIPK1 Q13546 1/20 0.35
MAPT P10636 1/20 0.35
KIF11 P52732 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
ALOX5 P09917 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
KMT2A Q03164 2/20 0.33
HPGDS O60760 1/20 0.33
CTSC P53634 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6717951 0.86 DAO (0.39) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL1233282 0.77 DAO (0.38) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL1421302 0.76 DAO (0.43) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL599752 0.76 DAO (0.43) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL7432298 0.76 DAO (0.43) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL1492740 0.76 DAO (0.43) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL73588 0.76 DAO (0.43) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL41617 0.76 DAO (0.43) CYP2C19DAOLMNAHCAR2TSHR
SCHEMBL21482457 0.76 CHRM3 (0.40) LMNATSHRMAPTALOX5PTGS1
SCHEMBL11649768 0.75 KIF11 (0.43) CYP2C19DAOLMNAHCAR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403159-A2 Imidazolyl-alkenoic acids SMITHKLINE BEECHAM CORPORATION (US) 1990-12-19 EP disclosed