Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360804 | 0.84 | ALDH1A1 (0.77) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| SCHEMBL70322 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| SCHEMBL156281 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| Hydrochloric Acid SCHEMBL2159177 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| Hydrochloric Acid SCHEMBL25289042 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| SCHEMBL2093835 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| SCHEMBL5345862 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| SCHEMBL2093831 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| Hydrochloric Acid SCHEMBL6645395 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNATSHRHIF1AHSD17B10 | |
| SCHEMBL2773146 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |