Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70322 | 0.86 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL10360804 | 0.86 | ALDH1A1 (0.77) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL156281 | 0.86 | ALDH1A1 (0.66) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL2093835 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL2093831 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL3150175 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL5545357 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL104703 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL6669086 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL5740093 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196198-B2 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-20040127487-A1 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2004-07-01 | — | — | US | disclosed |
| US-6710205-B2 | ANTIALLERGENS; ANTICANCER AGENTS; AUTOIMMUNE DISEASES; BONE DISORDERS; RHEUMATIC DISEASES; ANTIULCER AGENTS; SKIN DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-20030114435-A1 | Benzoic acid derivatives, processes for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1258473-A1 | BENZOIC ACID DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114435-A1 | Benzoic acid derivatives, processes for producing the same and drugs containing the same as the active ingredient | ALOX5, PDGFRB, ALOX15B | ALDH1A1 930/4885LMNA 2424/4885TSHR 4533/4885 |
| US-20040127487-A1 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | PDGFRB, ALOX5, ALOX15B | ALDH1A1 1003/4885LMNA 2014/4885TSHR 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.