Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | TK1 | P04183 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015162 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TK1HPGDCYP2C9CYP2C19 | |
| SCHEMBL7834509 | 0.80 | HPGD (0.55) | ALDH1A1HPGDKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL6722443 | 0.77 | HPGD (0.68) | ALDH1A1TK1HPGDMAPK1UPP1 | |
| SCHEMBL7219920 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TK1HPGDCYP2C9CYP2C19 | |
| SCHEMBL27691591 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TK1HPGDCYP2C9CYP2C19 | |
| SCHEMBL7541222 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TK1HPGDCYP2C9CYP2C19 | |
| SCHEMBL27691590 | 0.73 | ALDH1A1 (0.70) | ALDH1A1TK1HPGDCYP2C9CYP2C19 | |
| SCHEMBL27691593 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TK1HPGDCYP2C9CYP2C19 | |
| SCHEMBL30601622 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TK1HPGDCYP2C9CYP2C19 | |
| SCHEMBL2786159 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TK1HPGDCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673804-B1 | PREVENTING OR TREATING ARTHRITIS (PARTICULARLY OSTEOARTHRITIS) OR INHIBITING METASTASIS, INVASION OR GROWTH OF CANCER (PARTICULARLY BREAST CANCER) | SANKYO COMPANY, LIMITED (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1069110-A1 | SULFONAMIDE DERIVATIVES | Sankyo Company Limited (JP) | 2001-01-17 | — | — | EP | disclosed |