Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718627 | 1.00 | FFAR1 (0.60) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL6022668 | 1.00 | FFAR1 (0.60) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL4173511 | 0.93 | FFAR1 (0.51) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL5886652 | 0.87 | FFAR1 (0.63) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL6240991 | 0.85 | LOXL2 (0.47) | FFAR1FFAR4TNK2LOXL2 | |
| SCHEMBL9333090 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL2023915 | 0.84 | FFAR1 (0.70) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL9332907 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL9335934 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL9333536 | 0.83 | FFAR1 (0.68) | FFAR1FFAR4MMP2MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |