Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.85 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.85 |
| ▸ | BLM | P54132 | 3/20 | 0.85 |
| ▸ | POLB | P06746 | 2/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.82 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.76 |
| ▸ | PTPN12 | Q05209 | 3/20 | 0.76 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.76 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.76 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.76 |
| ▸ | MMP2 | P08253 | 1/20 | 0.76 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.76 |
| ▸ | DDX3X | O00571 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17319538 | 0.92 | MAPT (0.73) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL12008593 | 0.92 | KMT2A (1.00) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL12008765 | 0.91 | PTPN12 (0.91) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL12008591 | 0.91 | PTPN12 (0.80) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL17319559 | 0.90 | KMT2A (0.72) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL12008590 | 0.90 | KMT2A (1.00) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL12008979 | 0.88 | MEN1 (0.71) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL6886476 | 0.87 | MAPK1 (0.75) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL6886480 | 0.87 | MAPK1 (0.75) | MEN1KMT2ACTDSP1BLMPOLB | |
| SCHEMBL12008619 | 0.87 | PTPN7 (1.00) | MEN1KMT2ACTDSP1BLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183236-B2 | Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183236-B2 | Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-05-22 | — | — | US | disclosed |
| US-20090088420-A1 | COMPOUNDS WITH HIV-1 INTEGRASE INHIBITORY ACTIVITY AND USE THEREOF AS ANTI-HIV/AIDS THERAPEUTICS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-04-02 | — | — | US | disclosed |
| US-20090088420-A1 | COMPOUNDS WITH HIV-1 INTEGRASE INHIBITORY ACTIVITY AND USE THEREOF AS ANTI-HIV/AIDS THERAPEUTICS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088420-A1 | COMPOUNDS WITH HIV-1 INTEGRASE INHIBITORY ACTIVITY AND USE THEREOF AS ANTI-HIV/AIDS THERAPEUTICS | TYMP, IMPDH1, SAMHD1 | MEN1 4601/4885KMT2A 1477/4885CTDSP1 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.