Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6717492 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL492210 | 0.74 | CA12 (0.48) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8226360 | 0.74 | IDO1 (0.43) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL492013 | 0.73 | ELANE (0.49) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL1635139 | 0.73 | ELANE (0.49) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL492326 | 0.72 | KDM4E (0.52) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL6591576 | 0.72 | TLR4 (0.30) | ALDH1A1 | |
| SCHEMBL1176572 | 0.72 | TP53 (0.67) | MAPTKDM4EMAPK1SMN1; SMN2TP53 | |
| SCHEMBL2596428 | 0.69 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL21723240 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097728-A1 | Method for producing anellated tetrahydro-{1h}-triazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |
| EP-1196399-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZISOTHIAZOLE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001005775-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZISOTHIAZOLE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097728-A1 | Method for producing anellated tetrahydro-{1h}-triazoles | CBR1, CBR3, QSOX1 | ALDH1A1 709/4885MAPT 4497/4885KDM4E 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.