SCHEMBL672054

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL672286	0.82	JAK2 (0.41)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL2729216	0.78	ACHE (0.53)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL27885745	0.76	MAPT (0.33)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL27979934	0.75	ACHE (0.38)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL15894907	0.75	ACHE (0.42)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL1662568	0.75	ACHE (0.42)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL1703536	0.75	ACHE (0.42)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL15651008	0.74	ACHE (0.41)	MAPTLMNAALDH1A1PKML3MBTL1
	SCHEMBL28052532	0.73	CHRM2 (0.36)	LMNACHRM2HTR1AADRA2ACHRM1
	SCHEMBL5427247	0.73	CHRM2 (0.39)	LMNACHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.