Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27868138 | 0.81 | HPGD (0.40) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL27885745 | 0.78 | MAPT (0.33) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL2729216 | 0.77 | ACHE (0.53) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL27980022 | 0.76 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL672054 | 0.75 | MAPT (0.37) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL1662568 | 0.74 | ACHE (0.42) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL15894907 | 0.74 | ACHE (0.42) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL1703536 | 0.74 | ACHE (0.42) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL15651008 | 0.73 | ACHE (0.41) | ACHEMAPTLMNAALDH1A1PKM | |
| SCHEMBL17076744 | 0.71 | MEN1 (0.43) | ACHEMAPTLMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103987707-A | Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | HOFFMANN LA ROCHE | 2014-08-13 | — | — | CN | disclosed |