⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673922 | 0.94 | CA1 (0.35) | — | |
| SCHEMBL673199 | 0.91 | CA1 (0.39) | — | |
| SCHEMBL4453883 | 0.87 | — | — | |
| SCHEMBL15941586 | 0.77 | — | — | |
| SCHEMBL673840 | 0.76 | CA1 (0.33) | — | |
| Water SCHEMBL7648266 | 0.75 | ACHE (0.32) | — | |
| SCHEMBL10785137 | 0.73 | CA1 (0.31) | — | |
| SCHEMBL24862596 | 0.71 | EPHX1 (0.36) | — | |
| SCHEMBL3066085 | 0.71 | CA1 (0.37) | — | |
| SCHEMBL8435994 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025233849-A2 | MAPT siRNA AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2025-11-13 | — | — | WO | disclosed |
| WO-2025052316-A1 | SNCA siRNA AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2025-03-13 | — | — | WO | disclosed |
| EP-4493691-A2 | MAPT SIRNA AND USES THEREOF | JANSSEN Pharmaceutica NV (BE) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023175091-A2 | MAPT siRNA AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2023-09-21 | — | — | WO | disclosed |
| WO-2014124430-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2014-08-14 | — | — | WO | disclosed |
| US-20120252979-A1 | Process for Producing Blends of Syndiotactic, 1,2-Polybutadiene and Rubbery Elastomers | RADEMACHER CHRISTINE (US) | 2012-10-04 | — | — | US | disclosed |
| US-8067503-B2 | Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers | BRIDGESTONE CORPORATION (JP) | 2011-11-29 | — | — | US | disclosed |
| EP-1476480-B1 | POLYMERIZATION PROCESS FOR PREPARING SYNDIOTACTIC 1,2-POLYBUTADIENE | BRIDGESTONE CORP (JP) | 2009-07-22 | — | — | EP | disclosed |
| EP-0994128-B1 | Process and iron-based catalyst composition for the production of syndiotactic 1,2-polybutadiene | BRIDGESTONE CORP (JP) | 2007-08-01 | — | — | EP | disclosed |
| US-20070161748-A1 | PROCESS FOR PRODUCING BLENDS OF SYNDIOTACTIC, 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS | BRIDGESTONE CORPORATION | 2007-07-12 | — | — | US | disclosed |
| WO-2001032724-A1 | IRON-BASED CATALYST FOR PRODUCING OLIGOMERS OF CONJUGATED DIENES | BRIDGESTONE CORPORATION (JP) | 2001-05-10 | — | — | WO | disclosed |
| US-6211313-B1 | COORDINATION COMPOUND OF IRON CONTAINING COMPOUND, PHOSPHITE AND ORGANOALUMINUM COMPOUND | BRIDGESTONE CORPORATION (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6201080-B1 | CATALYTIC POLYMERIZATION OF BUTADIENE IN A SOLVENT | BRIDGESTONE CORPORATION (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6197888-B1 | FORMED BY COMBINING AN IRON-CONTAINING COMPOUND, A HYDROGEN PHOSPHITE, AND AN ORGANOALUMINUM COMPOUND. | BRIDGESTONE CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| WO-2000075201-A1 | MOLYBDENUM-BASED CATALYST COMPOSITION FOR POLYMERIZING CONJUGATED DIENES | BRIDGESTONE CORPORATION (JP) | 2000-12-14 | — | — | WO | disclosed |
| EP-0994127-A1 | Method of preparing syndiotactic 1,2-polybutadiene with a chromium-based catalyst system | Bridgestone Corporation (JP) | 2000-04-19 | — | — | EP | disclosed |
| EP-0994129-A1 | Iron-based catalyst composition and process for producing syndiotactic 1,2-polybutadiene | Bridgestone Corporation (JP) | 2000-04-19 | — | — | EP | disclosed |
| EP-0994128-A1 | Process and iron-based catalyst composition for the production of syndiotactic 1,2-polybutadiene | Bridgestone Corporation (JP) | 2000-04-19 | — | — | EP | disclosed |
| US-5919875-A | ORGANOALUMINUM HYDRIDE, ORGANIC HYDROGEN PHOSPHITE | BRIDGESTONE CORPORATION (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0926167-A1 | Preparation of syndiotactic 1,2-polybutadiene using a chromium-containing catalyst system | Bridgestone Corporation (JP) | 1999-06-30 | — | — | EP | disclosed |