SCHEMBL673840

SCHEMBL673840

CO[PH](=O)OC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ACHE P22303 1/20 0.33
ALDH1A1 P00352 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL7648266 0.98 ACHE (0.32) CA1CA2ACHEALDH1A1EPHX1
SCHEMBL673199 0.85 CA1 (0.39) CA1CA2ACHEEPHX1
SCHEMBL673922 0.82 CA1 (0.35) CA1CA2ACHEEPHX1
SCHEMBL672096 0.76
SCHEMBL24862596 0.76 EPHX1 (0.36) CA1CA2ACHEEPHX1
SCHEMBL13763439 0.75 CA1 (0.36) CA1CA2ACHEEPHX1
SCHEMBL28906085 0.73 CA1 (0.34) CA1CA2ACHEEPHX1
SCHEMBL28830281 0.73 CA1 (0.34) CA1CA2ACHEEPHX1
Cyclohexane SCHEMBL7128101 0.73
SCHEMBL3066085 0.72 CA1 (0.37) CA1CA2ACHEEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1234037-A Subsd. aminoalkane phosphonic acids NOVARTIS AG (CH) 1999-11-03 CN claimed
US-11692097-B2 Flame-retardant polyamide compositions with a high glow wire ignition temperature and use thereof CLARIANT INTERNATIONAL LTD (CH) 2023-07-04 US disclosed
US-20230130333-A1 METHOD FOR MANUFACTURING PHOSPHONATE ESTERS AND METHOD FOR MANUFACTURING PHOSPHATE ESTERS FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-04-27 US disclosed
US-20230130333-A1 METHOD FOR MANUFACTURING PHOSPHONATE ESTERS AND METHOD FOR MANUFACTURING PHOSPHATE ESTERS FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-04-27 US disclosed
US-20210363349-A1 FLAME-RETARDANT POLYAMIDE COMPOSITIONS WITH A HIGH GLOW WIRE IGNITION TEMPERATURE AND USE THEREOF CLARIANT PLASTICS & COATINGS LTD (CH) 2021-11-25 US disclosed
US-10172831-B2 Catalytic scavengers of organophosphates to potentiate butyrylcholinesterase (hBChE) as a catalytic bioscavenger and methods for making and using them THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-01-08 US disclosed
CN-107208042-A Fusion proteins, recombinant bacteria and methods of using recombinant bacteria 斯波根生物技术公司 2017-09-26 CN disclosed
US-20160256438-A1 CATALYTIC SCAVENGERS OF ORGANOPHOSPHATES TO POTENTIATE BUTYRYLCHOLINESTERASE (hBChE) AS A CATALYTIC BIOSCAVENGER AND METHODS FOR MAKING AND USING THEM UNIV CALIFORNIA (US) 2016-09-08 US disclosed
EP-3057582-A1 CATALYTIC SCAVENGERS OF ORGANOPHOSPHATES TO POTENTIATE BUTYRYLCHOLINESTERASE (BCHE) AS A CATALYTIC BIOSCAVENGER AND METHODS FOR MAKING AND USING THEM The Regents of the University of California (US) 2016-08-24 EP disclosed
WO-2015057822-A1 CATALYTIC SCAVENGERS OF ORGANOPHOSPHATES TO POTENTIATE BUTYRYLCHOLINESTERASE (BCHE) AS A CATALYTIC BIOSCAVENGER AND METHODS FOR MAKING AND USING THEM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-04-23 WO disclosed
US-6197888-B1 FORMED BY COMBINING AN IRON-CONTAINING COMPOUND, A HYDROGEN PHOSPHITE, AND AN ORGANOALUMINUM COMPOUND. BRIDGESTONE CORPORATION (JP) 2001-03-06 US disclosed
WO-2000075201-A1 MOLYBDENUM-BASED CATALYST COMPOSITION FOR POLYMERIZING CONJUGATED DIENES BRIDGESTONE CORPORATION (JP) 2000-12-14 WO disclosed
EP-0994127-A1 Method of preparing syndiotactic 1,2-polybutadiene with a chromium-based catalyst system Bridgestone Corporation (JP) 2000-04-19 EP disclosed
EP-0994129-A1 Iron-based catalyst composition and process for producing syndiotactic 1,2-polybutadiene Bridgestone Corporation (JP) 2000-04-19 EP disclosed
EP-0994128-A1 Process and iron-based catalyst composition for the production of syndiotactic 1,2-polybutadiene Bridgestone Corporation (JP) 2000-04-19 EP disclosed
CN-1242041-A Low moisture laundry detergent bar with improved physical properties PROCTER & GAMBLE (US) 2000-01-19 CN disclosed
US-5919875-A ORGANOALUMINUM HYDRIDE, ORGANIC HYDROGEN PHOSPHITE BRIDGESTONE CORPORATION (JP) 1999-07-06 US disclosed
EP-0926167-A1 Preparation of syndiotactic 1,2-polybutadiene using a chromium-containing catalyst system Bridgestone Corporation (JP) 1999-06-30 EP disclosed
CN-1038328-C Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents, and processes for their preparation DOW CHEMICAL CO (US) 1998-05-13 CN disclosed
CN-1074447-A Bicyclopolyazamacrocacidshosphonic acidshosphonic, its title complex and conjugate and their preparation method thereof as contrast medium DOW CHEMICAL CO (US) 1993-07-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10172831-B2 Catalytic scavengers of organophosphates to potentiate butyrylcholinesterase (hBChE) as a catalytic bioscavenger and methods for making and using them BCHE, ACHE, HMBS CA1 342/4885CA2 314/4885ACHE 2/4885
US-20160256438-A1 CATALYTIC SCAVENGERS OF ORGANOPHOSPHATES TO POTENTIATE BUTYRYLCHOLINESTERASE (hBChE) AS A CATALYTIC BIOSCAVENGER AND METHODS FOR MAKING AND USING THEM BCHE, ACHE, HMBS CA1 342/4885CA2 314/4885ACHE 2/4885
US-20230130333-A1 METHOD FOR MANUFACTURING PHOSPHONATE ESTERS AND METHOD FOR MANUFACTURING PHOSPHATE ESTERS PHOSPHO1, PHYKPL, PIK3CA CA1 775/4885CA2 1867/4885ACHE 1100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.