Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16802426 | 0.79 | MAPT (0.33) | MAPTALDH1A1GAANPC1LMNA | |
| SCHEMBL8001744 | 0.75 | MAPT (0.42) | MAPTALDH1A1GAANPC1LMNA | |
| SCHEMBL19293454 | 0.74 | — | — | |
| SCHEMBL11843782 | 0.72 | PRSS1 (0.30) | — | |
| SCHEMBL17896468 | 0.72 | MAPT (0.43) | MAPTALDH1A1GAANPC1LMNA | |
| SCHEMBL6393954 | 0.72 | MAPT (0.34) | MAPTALDH1A1GAANPC1LMNA | |
| SCHEMBL31547150 | 0.71 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL11858505 | 0.71 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL6719545 | 0.71 | ALDH1A1 (0.33) | ALDH1A1LMNATSHR | |
| SCHEMBL23293607 | 0.71 | MAPT (0.39) | MAPTALDH1A1GAANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033462-A2 | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO [2, 3-b] FURAN AND RELATED COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-04-22 | — | — | WO | disclosed |