Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31547150 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11858505 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6722036 | 0.71 | MAPT (0.42) | ALDH1A1LMNATSHR | |
| SCHEMBL2299371 | 0.70 | MAPT (0.32) | ALDH1A1 | |
| SCHEMBL7909118 | 0.70 | MAPT (0.32) | ALDH1A1 | |
| SCHEMBL11857778 | 0.70 | MAPT (0.32) | ALDH1A1 | |
| SCHEMBL11315477 | 0.69 | — | — | |
| SCHEMBL25348325 | 0.68 | — | — | |
| SCHEMBL4442810 | 0.68 | — | — | |
| SCHEMBL2302523 | 0.67 | CYP2D6 (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033462-A2 | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO [2, 3-b] FURAN AND RELATED COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-04-22 | — | — | WO | disclosed |