Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299221 | 0.71 | MAPT (0.31) | MAPT | |
| SCHEMBL9240436 | 0.65 | CHRM2 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7231521 | 0.64 | PLG (0.34) | MAPT | |
| SCHEMBL15095887 | 0.64 | CHRM2 (0.46) | MAPTALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL8515490 | 0.64 | CHRM2 (0.46) | MAPTALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL12700286 | 0.64 | CHRM2 (0.46) | MAPTALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL7515819 | 0.63 | — | — | |
| SCHEMBL31288930 | 0.63 | — | — | |
| SCHEMBL6722036 | 0.63 | MAPT (0.42) | MAPTALDH1A1GAANPC1LMNA | |
| SCHEMBL16878420 | 0.62 | CHRM2 (0.39) | TSHRCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033462-A2 | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO [2, 3-b] FURAN AND RELATED COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-04-22 | — | — | WO | disclosed |