SCHEMBL8515490

SCHEMBL8515490

C1COC(C2CCCO2)C1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
NOS2 P35228 1/20 0.38
MAPT P10636 1/20 0.32
PDK1 Q15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15095887 1.00 CHRM2 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL12700286 1.00 CHRM2 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL22788167 0.96
SCHEMBL24752922 0.93 CHRM2 (0.43) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL2175588 0.93
SCHEMBL18685786 0.90
SCHEMBL1803509 0.90
SCHEMBL176040 0.89 CHRM2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL16878420 0.89 CHRM2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL31247892 0.89 CHRM2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112679513-B Method for preparing key intermediate of koji Bei Ti 南通诺泰生物医药技术有限公司 2023-08-25 CN claimed
CN-112679512-B Trabectedin intermediate and preparation method thereof 南通诺泰生物医药技术有限公司 2023-08-25 CN claimed
CN-116136490-A Method for measuring electron spin life of semiconductor colloid nano material based on doping method 中国科学院大连化学物理研究所 2023-05-19 CN claimed
US-20250076305-A1 BODIPY-BASED DYES FOR DIGITAL SPATIAL PROTEOMICS TRUSTEES OF BOSTON UNIVERSITY (US) 2025-03-06 US disclosed
US-12206087-B2 Chemical prealkaliation of electrodes UWM RESEARCH FOUNDATION, INC. (US) 2025-01-21 US disclosed
CN-119053610-A 1,3,4, 7-Tetrahydro-2H-pyrrolo [3',2':5,6] pyrido [2,3-b ] [1,4] oxazepine Bcl-2 inhibitors 艾伯维公司 2024-11-29 CN disclosed
CN-113039675-B Chemical pre-alkalization of electrodes 威斯康星大学密尔沃基分校研究基金会公司 2024-10-22 CN disclosed
US-20240209007-A1 STABILIZED BORON ANIONS UNIV VIRGINIA PATENT FOUNDATION (US) 2024-06-27 US disclosed
CN-113754635-B Condensed ring compound and preparation method and application thereof 成都康弘药业集团股份有限公司 2024-06-21 CN disclosed
CN-118184688-A Preparation method of diisopropylamine silane 铜陵安德科铭电子材料科技有限公司 2024-06-14 CN disclosed
CN-118085301-A Aromatic silicone oil with reactivity, preparation method and application 山东共聚有机硅技术研究院有限公司 2024-05-28 CN disclosed
US-20100136438-A1 MAGNESIUM ION-CONTAINING NONAQUEOUS ELECTROLYTIC SOLUTION AND METHOD FOR MANUFACTURING THE SAME, AND ELECTROCHEMICAL DEVICE SONY CORPORATION (JP) 2010-06-03 US disclosed
US-7612009-B2 Process for homo-or copolymerization of conjugated olefines DOW GLOBAL TECHNOLOGIES, INC. (US) 2009-11-03 US disclosed
US-20090131705-A1 Practical, Cost-Effective Synthesis of Ubiquinones ZYMES, LLC 2009-05-21 US disclosed
US-20080275255-A1 Stabilized Borane-Tetrahydrofuran Complex SIGMA-ALDRICH CO. (US) 2008-11-06 US disclosed
US-20080207853-A1 Precatalysts useful in polyolefin polymerization reactions THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2008-08-28 US disclosed
US-7312228-B2 Cytotoxic indeno and isoindoloisoquinolones PURDUE RESEARCH FOUNDATION (US) 2007-12-25 US disclosed
US-7301045-B2 Method for preparing ester condensate JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2007-11-27 US disclosed
US-20070260076-A1 Practical, Cost-Effective Synthesis of Ubiquinones ZYMES, LLC 2007-11-08 US disclosed
US-20070203111-A1 Cycloalkylamines as monoamine reuptake inhibitors SEPRACOR INC. (US) 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250076305-A1 BODIPY-BASED DYES FOR DIGITAL SPATIAL PROTEOMICS ANXA2, FABP2, CHAMP1 CHRM2 4233/4885CHRM4 4269/4885CHRM5 4547/4885
US-20070260076-A1 Practical, Cost-Effective Synthesis of Ubiquinones SQOR, NDUFS6, NDUFS5 CHRM2 3761/4885CHRM4 2661/4885CHRM5 2736/4885
US-20090131705-A1 Practical, Cost-Effective Synthesis of Ubiquinones SQOR, NDUFS6, NDUFS5 CHRM2 3761/4885CHRM4 2661/4885CHRM5 2736/4885
US-20070203111-A1 Cycloalkylamines as monoamine reuptake inhibitors SLC18A2, SLC6A2, SLC18A3 CHRM2 111/4885CHRM4 74/4885CHRM5 69/4885
US-20080275255-A1 Stabilized Borane-Tetrahydrofuran Complex BPTF, TBCB, RTF1 CHRM2 4799/4885CHRM4 4770/4885CHRM5 4758/4885
US-20240209007-A1 STABILIZED BORON ANIONS BRSK2, BRSK1, BOLA2; BOLA2B CHRM2 2402/4885CHRM4 1916/4885CHRM5 3614/4885
US-20080207853-A1 Precatalysts useful in polyolefin polymerization reactions PPOX, PORCN, PTGES CHRM2 4351/4885CHRM4 3209/4885CHRM5 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.