Diphenylsulfane

Diphenylsulfane

SCHEMBL672237

O=S(=O)(Oc1ccc(Cl)cc1)C(F)(F)F.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.51
PPARG P37231 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
STS P08842 1/20 0.43
CHRNA7 P36544 1/20 0.41
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
ENPP3 O14638 2/20 0.38
ENPP1 P22413 2/20 0.38
PGR P06401 3/20 0.37
CXCR2 P25025 2/20 0.37
HTT P42858 2/20 0.36
MAPT P10636 2/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
PPARA Q07869 1/20 0.36
CXCR1 P25024 1/20 0.36
XBP1 P17861 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL673319 0.90 STS (0.53) TDP1CA1CA2CA9STS
SCHEMBL2569852 0.90 STS (0.53) TDP1CA1CA2CA9STS
SCHEMBL2941459 0.86 CA2 (0.57) TDP1PPARGCA1CA2CA9
Diphenylsulfane SCHEMBL672234 0.85 CA1 (0.51) CA1CA2CA9STSPGR
Diphenylsulfane SCHEMBL674158 0.85 STS (0.44) CA1CA2CA9STSCXCR2
Biphenyl SCHEMBL21461722 0.85 STS (0.49) TDP1CA1CA2CA9STS
Biphenyl SCHEMBL17420890 0.84 STS (0.47) CA1CA2CA9STSADORA2A
Diphenylsulfane SCHEMBL3275151 0.84 CA1 (0.44) TDP1CA1CA2CA9STS
Diphenylsulfane SCHEMBL5698067 0.84 CA1 (0.44) CA1CA2CA9STSCXCR2
Diphenylsulfane SCHEMBL672139 0.84 PPARG (0.45) TDP1PPARGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10068200-B1 Business and data processing system for providing mass spectrometric services MASS INSIGHT INC (US) 2018-09-04 US disclosed
US-9460904-B1 Methods, apparatus, and compositions for mass spectrometry GREVING MATTHEW PAUL (US) 2016-10-04 US disclosed
EP-2591060-A2 COATING SYSTEMS CAPABLE OF FORMING AMBIENTLY CURED HIGHLY DURABLE HYDROPHOBIC COATINGS ON SUBSTRATES Luna Innovations Incorporated (US) 2013-05-15 EP disclosed
US-20130109261-A1 COATING SYSTEMS CAPABLE OF FORMING AMBIENTLY CURED HIGHLY DURABLE HYDROPHOBIC COATINGS ON SUBSTRATES LUNA INNOVATIONS (US) 2013-05-02 US disclosed
WO-2012024005-A2 COATING SYSTEMS CAPABLE OF FORMING AMBIENTLY CURED HIGHLY DURABLE HYDROPHOBIC COATINGS ON SUBSTRATES LUNA INNOVATIONS INCORPORATED (US) 2012-02-23 WO disclosed