Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718390 | 0.95 | TDP1 (0.49) | TDP1PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL6714897 | 0.83 | PPARG (0.50) | TDP1PPARGPPARAMAPK1PTGES | |
| SCHEMBL6718057 | 0.81 | TDP1 (0.54) | TDP1PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL6718054 | 0.80 | PPARG (0.50) | TDP1PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL6717768 | 0.80 | TDP1 (0.53) | TDP1PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL6716007 | 0.79 | TDP1 (0.56) | TDP1PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL6713072 | 0.79 | PPARG (0.53) | TDP1PPARGPPARAPPARDMAPK1 | |
| SCHEMBL6617763 | 0.76 | PPARG (0.46) | TDP1PPARGPPARAL3MBTL1MAPK1 | |
| SCHEMBL6714958 | 0.72 | MEN1 (0.51) | TDP1PPARGPPARAPPARDL3MBTL1 | |
| SCHEMBL27605408 | 0.72 | TDP1 (0.61) | TDP1PPARGPPARAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | TDP1 4224/4885PPARG 23/4885PPARA 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.