Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944745 | 0.82 | NPSR1 (0.41) | NPSR1KEAP1F13A1POLBPTGER1 | |
| SCHEMBL10784805 | 0.81 | NPSR1 (0.47) | NPSR1KEAP1POLBPTGER1PTGER4 | |
| SCHEMBL20434221 | 0.78 | NPSR1 (0.53) | NPSR1POLBPTGER1PTGER4PTGER3 | |
| SCHEMBL4814721 | 0.78 | APEX1 (0.55) | NPSR1POLBFFAR1ITGB3ITGAV | |
| SCHEMBL5500307 | 0.78 | SMN1; SMN2 (0.53) | NPSR1FFAR1HPGDFFAR4GPR17 | |
| SCHEMBL18397695 | 0.78 | APEX1 (0.51) | NPSR1KEAP1POLBFFAR1HPGD | |
| SCHEMBL29151337 | 0.78 | PTPN1 (0.42) | HPGDHMGB1CXCL12ALDH1A1HSD17B10 | |
| SCHEMBL28353593 | 0.76 | HMGB1 (0.37) | HPGDHMGB1CXCL12ALDH1A1HSD17B10 | |
| SCHEMBL29062 | 0.76 | FOLH1 (0.66) | NPSR1KEAP1PTGER1PTGER4PTGER3 | |
| SCHEMBL7095783 | 0.76 | NPSR1 (0.45) | NPSR1KEAP1POLBPTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| EP-2596082-B1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2596082-B1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2596082-A1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | Merck Patent GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012022388-A1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012022388-A1 | POLYMER-STABILIZED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |