Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | F13A1 | P00488 | 3/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672247 | 0.82 | NPSR1 (0.56) | NPSR1POLBPTGER1PTGER4PTGER3 | |
| SCHEMBL17693400 | 0.76 | PARP1 (0.46) | POLBKEAP1FFAR1FFAR4 | |
| SCHEMBL17790521 | 0.75 | NPSR1 (0.42) | NPSR1POLBLTB4RPTGER1PTGER4 | |
| SCHEMBL17790470 | 0.75 | NPSR1 (0.42) | NPSR1POLBLTB4RPTGER1PTGER4 | |
| SCHEMBL19248512 | 0.73 | FFAR1 (0.56) | KEAP1FFAR1FFAR4 | |
| SCHEMBL19248509 | 0.72 | FFAR4 (0.41) | KEAP1FFAR1FFAR4CYP2C19 | |
| Phenyl Propionic Acid SCHEMBL30136446 | 0.70 | KEAP1 (0.66) | KEAP1FFAR1FFAR4 | |
| SCHEMBL14409075 | 0.70 | LTB4R (0.38) | NPSR1POLBLTB4RKEAP1FFAR1 | |
| SCHEMBL17693428 | 0.69 | ALDH1A1 (0.49) | NPSR1POLBPTGER4KEAP1FFAR1 | |
| SCHEMBL383965 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |