SCHEMBL6722647

SCHEMBL6722647

COc1ccc(-c2ncc[nH]2)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 4/20 0.55
ADRA2A P08913 1/20 0.46
ADRA2C P18825 1/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA1B P35368 1/20 0.46
TLK2 Q86UE8 2/20 0.44
MC4R P32245 1/20 0.44
SMPD3 Q9NY59 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PDGFRB P09619 1/20 0.41
CDKN1A P38936 1/20 0.40
CHRNA7 P36544 1/20 0.40
PRKAB2 O43741 2/20 0.40
PRKAG1 P54619 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27303150 0.84 CYP1A2 (0.47) AMY1AMC4RCYP1A2CYP3A4CYP2D6
SCHEMBL8542548 0.82 ADRA2A (0.57) AMY1AADRA2AADRA2CADRA1DADRA1A
SCHEMBL6003238 0.82 PDE2A (0.55) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL11203475 0.82 NOTUM (0.54) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL31559158 0.81 SMPD3 (0.50) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL8541036 0.81 SMPD3 (0.50) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL31429681 0.81 NOTUM (0.53) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL8540690 0.81 ADRA2A (0.46) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL14316064 0.80 AMY1A (0.36) AMY1ATLK2MC4RCYP1A2CYP3A4
SCHEMBL10926149 0.79 ADRA2A (0.44) ADRA2AADRA2CADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8182975-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-05-22 US disclosed
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-8092978-B2 Positive resist composition for electron beam, X-ray or EUV and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-01-10 US disclosed
US-8084187-B2 Resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2011-12-27 US disclosed
US-7989137-B2 Resist composition and pattern-forming method using the same FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-7923199-B2 Using a sulfonium acid generator that forms a fluorine-substituted sulfonic acid compound; improved in the exposure latitude, pitch dependency and line edge roughness and enhanced in the sensitivity and resolution at the exposure with EUV light FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-7858289-B2 Positive resist composition for electron beam, X-ray or EUV and pattern forming method using the same FUJIFILM CORPORATION (JP) 2010-12-28 US disclosed
US-7799506-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2010-09-21 US disclosed
US-7615330-B2 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-20090253070-A1 RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-10-08 US disclosed
US-20090246685-A1 POSITIVE RESIST COMPOSITION FOR ELECTRON BEAM, X-RAY OR EUV AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090111047-A1 POSITIVE RESIST COMPOSITION FOR ELECTRON BEAM, X-RAY OR EUV AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-30 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087776-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087789-A1 RESIST COMPOSITION AND PATTERN-FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20080248419-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed
US-20070224540-A1 Positive resist composition and pattern formation method using the same FUJIFILM CORPORATION (JP) 2007-09-27 US disclosed