SCHEMBL6723404

SCHEMBL6723404

CC1=Cc2c(cccc2C(C)(C)C)C1C[SiH2]CC1C(C)=Cc2c1cccc2C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3154189 0.80 MEN1 (0.31)
SCHEMBL1452276 0.78 GABRA1 (0.30) GABRA1GABRB2CA2
SCHEMBL1452451 0.78 KDM4E (0.31) GABRA1GABRB2CA2
SCHEMBL1451771 0.78 GABRA1 (0.30) GABRA1GABRB2CA2
SCHEMBL1453594 0.78 GABRA1 (0.30) GABRA1GABRB2CA2
SCHEMBL4003324 0.76 BRD4 (0.34)
SCHEMBL22411214 0.76 BRD4 (0.34)
SCHEMBL6234189 0.76 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL6240510 0.75 GABRA1 (0.33) GABRA1GABRB2CA2
SCHEMBL20338970 0.74 BRD4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 EP claimed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
US-5914376-A Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof TARGOR GMBH (DE) 1999-06-22 US claimed
US-20040030050-A1 Polypropylene films EXXONMOBIL CHEMICAL PATENTS INC. 2004-02-12 US disclosed
EP-1373337-A2 PROPYLENE POLYMERS FOR FILMS Exxonmobil Chemical Patents Inc. (US) 2004-01-02 EP disclosed
EP-1263909-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2002-12-11 EP disclosed
WO-2002070572-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
WO-2002070570-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
WO-2001046277-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-06-28 WO disclosed
EP-1109839-A1 HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2001-06-27 EP disclosed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US disclosed
WO-2000018773-A1 CHEMICAL COMPOUND TARGOR GMBH (DE) 2000-04-06 WO disclosed
WO-2000012565-A1 HIGHLY ACTIVE SUPPORTED CATALYST COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 2000-03-09 WO disclosed