SCHEMBL3154189

SCHEMBL3154189

CC1=Cc2c(C)cccc2C1C[SiH2]CC1C(C)=Cc2c(C)cccc21

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6650592 0.85 PBRM1 (0.32) SLC6A2SLC6A4SLC6A3
SCHEMBL7032913 0.83 ALDH1A1 (0.33) MEN1ALDH1A1KMT2ASLC6A2SLC6A4
SCHEMBL6239232 0.81 MEN1 (0.32) MEN1ALDH1A1KMT2A
SCHEMBL6234189 0.81 GABRA1 (0.33)
SCHEMBL6723404 0.80 GABRA1 (0.33)
SCHEMBL6240510 0.80 GABRA1 (0.33) SLC6A2
SCHEMBL1241178 0.79 PDCD1 (0.36)
SCHEMBL3997056 0.79 GABRA1 (0.33) SLC6A2
SCHEMBL3997096 0.78 PDCD1 (0.35)
SCHEMBL4626569 0.78 KIF11 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US claimed
US-5914376-A Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof TARGOR GMBH (DE) 1999-06-22 US claimed
EP-1270614-B1 Copolymers containing propylene and alpha-olefin comonomer BASELL POLYOLEFINE GMBH (DE) 2010-01-27 EP disclosed
WO-2005003184-A1 POLYMERIZATION PROCESSES USING ANTISTATIC AGENTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-01-13 WO disclosed
EP-1315858-A1 POLYPROPYLENE FIBERS AND FABRICS Exxonmobil Chemical Patents Inc. (US) 2003-06-04 EP disclosed
EP-1313782-A1 POLYPROPYLENE POLYMERS Exxonmobil Chemical Patents Inc. (US) 2003-05-28 EP disclosed
EP-1311593-A2 POLYPROPYLENE FILMS Exxonmobil Chemical Patents Inc. (US) 2003-05-21 EP disclosed
EP-0889059-B1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 2003-02-12 EP disclosed
EP-1263909-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2002-12-11 EP disclosed
EP-0773204-B1 Process for the preparation of an indene and use thereof for the preparation of metallocenes BASELL POLYOLEFINE GMBH (DE) 2002-12-04 EP disclosed
WO-2002070570-A2 PROPYLENE POLYMERS FOR FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-09-12 WO disclosed
WO-2002016480-A2 POLYPROPYLENE FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO disclosed
WO-2001046277-A2 POLYPROPYLENE-BASED ADHESIVE COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-06-28 WO disclosed
WO-2001036497-A1 SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO disclosed
WO-2001032757-A1 FOAMABLE POLYPROPYLENE POLYMERS AND THEIR USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-05-10 WO disclosed
US-6143686-A FOR ADDITION POLYMERIZATION OF ALPHA OLEFINS, SUCH AS PROPYLENE TO PRODUCE STEREOSPECIFIC POLMER EXXON CHEMICAL PATENTS, INC. (US) 2000-11-07 US disclosed
US-5965678-A Catalyst system based on monoazadiene metal complexes BAYER AG (DE) 1999-10-12 US disclosed
EP-0889059-A1 Catalyst based on monoazadiene metal complexes BAYER AG (DE) 1999-01-07 EP disclosed
EP-0773204-A2 Process for the preparation of an indene and use thereof for the preparation of metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-14 EP disclosed
EP-0530647-A1 Metallocenes, catalysts containing these and process for the manufacture of olefinic polymers by using these catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed