Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 5/20 | 0.51 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723913 | 0.98 | CHKA (0.49) | CHKAPDE5AMAOAKMOABCG2 | |
| SCHEMBL6723947 | 0.98 | CHKA (0.53) | CHKAPDE5AMAOAGSK3BABCG2 | |
| SCHEMBL6723789 | 0.96 | CHKA (0.49) | CHKAPDE5AMAOAKMOGSK3B | |
| SCHEMBL6723531 | 0.96 | CHKA (0.49) | CHKAPDE5AMAOAKMOGSK3B | |
| SCHEMBL6723961 | 0.96 | CHKA (0.51) | CHKAPDE5AMAOAGSK3BABCG2 | |
| SCHEMBL6723762 | 0.96 | CHKA (0.50) | CHKAPDE5AMAOAABCG2ALDH1A1 | |
| SCHEMBL20091188 | 0.94 | CHKA (0.47) | CHKAPDE5AMAOAGSK3BNR3C2 | |
| SCHEMBL6724123 | 0.94 | CHKA (0.46) | CHKAPDE5AMAOAKMOABCG2 | |
| SCHEMBL6723784 | 0.94 | CHKA (0.50) | CHKAPDE5AMAOAGSK3BNR3C2 | |
| SCHEMBL6723434 | 0.94 | CHKA (0.50) | CHKAPDE5AMAOAGSK3BNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178216-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178216-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-03-19 | — | — | US | disclosed |
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | CRY1, GRK1, CRY2 | CHKA 4185/4885PDE5A 3174/4885MAOA 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.