SCHEMBL6724922

SCHEMBL6724922

CCCCOC(=O)c1ccc(NC(=O)NS(=O)(=O)c2cccc(C)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.58
FBP1 P09467 9/20 0.57
HPGD P15428 1/20 0.54
RECQL P46063 1/20 0.54
MAPT P10636 3/20 0.53
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
KMT2A Q03164 1/20 0.53
MAPK14 Q16539 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 2/20 0.48
NLRP3 Q96P20 1/20 0.48
TP53 P04637 1/20 0.48
KCNA1 Q09470 1/20 0.48
KCNAB1 Q14722 1/20 0.48
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6720872 0.95 FBP1 (0.55) POLBFBP1HPGDMAPTALDH1A1
SCHEMBL6725015 0.95 FBP1 (0.55) POLBFBP1HPGDMAPTALDH1A1
SCHEMBL6731776 0.94 FBP1 (0.54) POLBFBP1HPGDMAPTMEN1
SCHEMBL6325357 0.91 SMN1; SMN2 (0.58) POLBFBP1HPGDMAPTMEN1
SCHEMBL1395597 0.87 HPGD (0.58) POLBHPGDRECQLMAPTMEN1
SCHEMBL6321812 0.87 FBP1 (0.54) FBP1HPGDMAPTMEN1KMT2A
SCHEMBL6324516 0.87 FBP1 (0.54) FBP1HPGDMAPTMEN1KMT2A
SCHEMBL6331017 0.87 FBP1 (0.54) FBP1HPGDMAPTMEN1KMT2A
SCHEMBL1931132 0.85 FBP1 (0.54) FBP1HPGDMEN1KMT2ASMN1; SMN2
SCHEMBL1929181 0.85 FBP1 (0.54) FBP1HPGDKMT2ASMN1; SMN2NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1044824-B1 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO (JP) 2004-05-12 EP disclosed
US-6677472-B2 AS COLOR-DEVELOPING AGENT; HIGH WHITENESS AND RESISTANCE TO COLOR FORMATION UNDER HIGH TEMPERATURE OJI PAPER CO., LTD. (JP) 2004-01-13 US disclosed
US-6486094-B1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-11-26 US disclosed
US-20020065196-A1 Bis (arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER CO., LTD. (JP) 2002-05-30 US disclosed
EP-1044824-A2 Bis(arylsulfonylaminocarbonylaminobenzoate) compounds and thermosensitive recording materials containing same OJI PAPER COMPANY LIMITED (JP) 2000-10-18 EP disclosed