Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12690712 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL2745022 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL12207274 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL12146745 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL12207270 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL12146594 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL12207627 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL12690611 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL4750680 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA | |
| SCHEMBL12146744 | 1.00 | KDM4E (0.58) | KDM4EL3MBTL1LMNATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178216-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178216-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-03-19 | — | — | US | disclosed |
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | CRY1, GRK1, CRY2 | KDM4E 2006/4885L3MBTL1 826/4885LMNA 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.