SCHEMBL6725299

SCHEMBL6725299

O=C(c1ncc(-c2cccc[n+]2[O-])s1)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.55
F2 P00734 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6736769 0.87 F10 (0.53) F10F2
SCHEMBL6787177 0.86 F10 (0.51) F10F2
SCHEMBL6725557 0.85 F10 (0.55) F10F2SMN1; SMN2LMNAALDH1A1
SCHEMBL6733194 0.85 ATM (0.53) F10F2SMN1; SMN2LMNAALDH1A1
SCHEMBL6729991 0.84 F10 (0.53) F10F2SMN1; SMN2LMNAALDH1A1
SCHEMBL6726703 0.84 F10 (0.49) F10F2SMN1; SMN2LMNAALDH1A1
SCHEMBL6734559 0.83 SMN1; SMN2 (0.56) F10F2SMN1; SMN2LMNAALDH1A1
SCHEMBL6727877 0.83 ALDH1A1 (0.58) F10F2SMN1; SMN2LMNAALDH1A1
Hydrochloric Acid SCHEMBL6729777 0.82 SMN1; SMN2 (0.56) F10F2SMN1; SMN2LMNAALDH1A1
SCHEMBL6730388 0.82 ALDH1A1 (0.53) F10F2SMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885F2 1/4885SMN1; SMN2 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.